Kidney bear an important responsibility of filter blood, so it is particularly vulnerable to damage excessive toxins in the blood, which is why someone is too much cause of renal failure after the treatment. So, how do we make drug research and development of more secure? Under normal circumstances, the researchers will experiment in some mammals, but the result of the experiment and human himself or is very different, so everyone can only "speculation" roughly corresponding dose "" human security.
"On kidney function simulation has been developed at the university of Michigan
Don't, the better way? The good news is that researchers at the university of Michigan, has just launched a can save more lives "on kidney function analog chips" (kidney - on - a - chip).
The device can be more closely simulate delay drug in human blood through the kidneys and the processed results, each animal has a slightly different, but the chips make delay researchers can make a series of more rigorous testing.
Its appearance looks like an ordinary glass slide, but contains a cultivated human kidney cells and infiltration of polyester film, in the form of a sandwich between the top and bottom.
Top can be injected into different concentrations of drug dosage, and then leads to microfluidic channels, through osmosis membrane and kidney cells, finally arrived at the bottom. Then, the researchers can check the cells under a microscope.